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Mechanistic insights into DNA binding and cleavage by a compact type I-F CRISPR-Cas system in bacteriophage
CRISPR-Cas systems are widespread adaptive antiviral systems used in prokaryotes. Some phages, in turn, although have small genomes can economize the use of genetic space to encode compact or incomplete CRISPR-Cas systems to inhibit the host and establish infection. Phage ICP1, infecting Vibrio chol...
Autores principales: | Zhang, Manling, Peng, Ruchao, Peng, Qi, Liu, Sheng, Li, Zhiteng, Zhang, Yuqin, Song, Hao, Yang, Jia, Xing, Xiao, Wang, Peiyi, Qi, Jianxun, Gao, George F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161043/ https://www.ncbi.nlm.nih.gov/pubmed/37094126 http://dx.doi.org/10.1073/pnas.2215098120 |
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