Targeting SWI/SNF ATPases in H3.3K27M diffuse intrinsic pontine gliomas

Diffuse midline gliomas (DMGs) including diffuse intrinsic pontine gliomas (DIPGs) bearing lysine-to-methionine mutations in histone H3 at lysine 27 (H3K27M) are lethal childhood brain cancers. These tumors harbor a global reduction in the transcriptional repressive mark H3K27me3 accompanied by an i...

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Detalles Bibliográficos
Autores principales: Mota, Mateus, Sweha, Stefan R., Pun, Matt, Natarajan, Siva Kumar, Ding, Yujie, Chung, Chan, Hawes, Debra, Yang, Fusheng, Judkins, Alexander R., Samajdar, Susanta, Cao, Xuhong, Xiao, Lanbo, Parolia, Abhijit, Chinnaiyan, Arul M., Venneti, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161095/
https://www.ncbi.nlm.nih.gov/pubmed/37094128
http://dx.doi.org/10.1073/pnas.2221175120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161095/
https://www.ncbi.nlm.nih.gov/pubmed/37094128
http://dx.doi.org/10.1073/pnas.2221175120

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