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M(1)-selective muscarinic allosteric modulation enhances cognitive flexibility and effective salience in nonhuman primates

Acetylcholine (ACh) in cortical neural circuits mediates how selective attention is sustained in the presence of distractors and how flexible cognition adjusts to changing task demands. The cognitive domains of attention and cognitive flexibility might be differentially supported by the M(1) muscari...

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Detalles Bibliográficos
Autores principales: Hassani, Seyed A., Neumann, Adam, Russell, Jason, Jones, Carrie K., Womelsdorf, Thilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161096/
https://www.ncbi.nlm.nih.gov/pubmed/37104474
http://dx.doi.org/10.1073/pnas.2216792120