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Malic Enzyme 1 as a Novel Anti‐Ferroptotic Regulator in Hepatic Ischemia/Reperfusion Injury

Ferroptosis has been linked to the pathogenesis of hepatic injury induced by ischemia/reperfusion (I/R). However, the mechanistic basis remains unclear. In this study, by using a mouse model of hepatic I/R injury, it is observed that glutathione (GSH) and cysteine depletion are associated with defic...

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Detalles Bibliográficos
Autores principales: Fang, Xuexian, Zhang, Jiawei, Li, You, Song, Yijing, Yu, Yingying, Cai, Zhaoxian, Lian, Fuzhi, Yang, Jun, Min, Junxia, Wang, Fudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161122/
https://www.ncbi.nlm.nih.gov/pubmed/36840630
http://dx.doi.org/10.1002/advs.202205436