Small Molecule Decoys of Aggregation for Elimination of Aβ-Peptide Toxicity

[Image: see text] Several lines of evidence suggest that a characteristic of the neuropathology of Alzheimer’s disease (AD) is the aggregation of the amyloid beta peptides (Aβ), fragments of the human amyloid precursor protein (hAPP). The dominating species are the Aβ40 and Aβ42 fragments with 40 an...

Descripción completa

Detalles Bibliográficos
Autores principales: Oasa, Sho, Kouznetsova, Valentina L., Tiiman, Ann, Vukojević, Vladana, Tsigelny, Igor F., Terenius, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161222/
https://www.ncbi.nlm.nih.gov/pubmed/37058367
http://dx.doi.org/10.1021/acschemneuro.2c00649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161222/
https://www.ncbi.nlm.nih.gov/pubmed/37058367
http://dx.doi.org/10.1021/acschemneuro.2c00649

Ejemplares similares