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Small Molecule Decoys of Aggregation for Elimination of Aβ-Peptide Toxicity
[Image: see text] Several lines of evidence suggest that a characteristic of the neuropathology of Alzheimer’s disease (AD) is the aggregation of the amyloid beta peptides (Aβ), fragments of the human amyloid precursor protein (hAPP). The dominating species are the Aβ40 and Aβ42 fragments with 40 an...
Autores principales: | Oasa, Sho, Kouznetsova, Valentina L., Tiiman, Ann, Vukojević, Vladana, Tsigelny, Igor F., Terenius, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161222/ https://www.ncbi.nlm.nih.gov/pubmed/37058367 http://dx.doi.org/10.1021/acschemneuro.2c00649 |
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