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Yes-associated protein inhibition ameliorates liver fibrosis and acute and chronic liver failure by decreasing ferroptosis and necroptosis

BACKGROUND/AIMS: This study aims to determine which cell death modes contribute most in the progression of cirrhosis and acute-on-chronic liver failure (ACLF), and to investigate whether Yes associated protein (YAP) affects the disease process by regulating cell death. MATERIALS AND METHODS: 30C57BL...

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Detalles Bibliográficos
Autores principales: Zhao, Wen, Lei, Miao, Li, Jinfeng, Zhang, Hailin, Zhang, Hongkun, Han, Yuxin, Ba, Zhiwei, Zhang, Manli, Li, Dongdong, Liu, Chuanmiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161368/
https://www.ncbi.nlm.nih.gov/pubmed/37151632
http://dx.doi.org/10.1016/j.heliyon.2023.e15075