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EvoAug: improving generalization and interpretability of genomic deep neural networks with evolution-inspired data augmentations

Deep neural networks (DNNs) hold promise for functional genomics prediction, but their generalization capability may be limited by the amount of available data. To address this, we propose EvoAug, a suite of evolution-inspired augmentations that enhance the training of genomic DNNs by increasing gen...

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Detalles Bibliográficos
Autores principales: Lee, Nicholas Keone, Tang, Ziqi, Toneyan, Shushan, Koo, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161416/
https://www.ncbi.nlm.nih.gov/pubmed/37143118
http://dx.doi.org/10.1186/s13059-023-02941-w