Systematic screening identifies ABCG2 as critical factor underlying synergy of kinase inhibitors with transcriptional CDK inhibitors

BACKGROUND: Triple-negative breast cancer (TNBC) is a subtype of breast cancer with limited treatment options and poor clinical prognosis. Inhibitors of transcriptional CDKs are currently under thorough investigation for application in the treatment of multiple cancer types, including breast cancer....

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Detalles Bibliográficos
Autores principales: van der Noord, Vera E., van der Stel, Wanda, Louwerens, Gijs, Verhoeven, Danielle, Kuiken, Hendrik J., Lieftink, Cor, Grandits, Melanie, Ecker, Gerhard F., Beijersbergen, Roderick L., Bouwman, Peter, Le Dévédec, Sylvia E., van de Water, Bob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161439/
https://www.ncbi.nlm.nih.gov/pubmed/37147730
http://dx.doi.org/10.1186/s13058-023-01648-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161439/
https://www.ncbi.nlm.nih.gov/pubmed/37147730
http://dx.doi.org/10.1186/s13058-023-01648-x

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