Promoting AMPK/SR-A1-mediated clearance of HMGB1 attenuates chemotherapy-induced peripheral neuropathy

BACKGROUND: Chemotherapy-induced peripheral neuropathy (CIPN) is a serious side effect of chemotherapy with poorly understood mechanisms and few treatments. High-mobility group box 1 (HMGB1)-induced neuroinflammation is the main cause of CIPN. Here, we aimed to illustrate the role of the macrophage...

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Detalles Bibliográficos
Autores principales: Yang, Xing, Jia, Rumeng, Hu, Fan, Fan, Wen, Lin, Tongtong, Zhang, Xiaotao, Xu, Chenjie, Ruan, Shirong, Jiang, Chunyi, Li, Yan, Pan, Cailong, Yang, Yang, Hu, Liang, Chen, Qi, Liu, Wen-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161452/
https://www.ncbi.nlm.nih.gov/pubmed/37143083
http://dx.doi.org/10.1186/s12964-023-01100-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161452/
https://www.ncbi.nlm.nih.gov/pubmed/37143083
http://dx.doi.org/10.1186/s12964-023-01100-9

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