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Opinion: more mouse models and more translation needed for ALS

Amyotrophic lateral sclerosis is a complex disorder most of which is ‘sporadic’ of unknown origin but approximately 10% is familial, arising from single mutations in any of more than 30 genes. Thus, there are more than 30 familial ALS subtypes, with different, often unknown, molecular pathologies le...

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Detalles Bibliográficos
Autores principales: Fisher, Elizabeth M.C., Greensmith, Linda, Malaspina, Andrea, Fratta, Pietro, Hanna, Michael G., Schiavo, Giampietro, Isaacs, Adrian M., Orrell, Richard W., Cunningham, Thomas J., Arozena, Abraham Acevedo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161557/
https://www.ncbi.nlm.nih.gov/pubmed/37143081
http://dx.doi.org/10.1186/s13024-023-00619-2