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Robust identification of regulatory variants (eQTLs) using a differential expression framework developed for RNA-sequencing
BACKGROUND: A gap currently exists between genetic variants and the underlying cell and tissue biology of a trait, and expression quantitative trait loci (eQTL) studies provide important information to help close that gap. However, two concerns that arise with eQTL analyses using RNA-sequencing data...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161580/ https://www.ncbi.nlm.nih.gov/pubmed/37143150 http://dx.doi.org/10.1186/s40104-023-00861-0 |