Reduced pain sensitivity of episodic pain syndrome model mice carrying a Nav1.9 mutation by ANP-230, a novel sodium channel blocker

The sodium channel Nav1.9 is expressed in the sensory neurons of small diameter dorsal root ganglia that transmit pain signals, and gain-of-function Nav1.9 mutations have been associated with both painful and painless disorders. We initially determined that some Nav1.9 mutations are responsible for...

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Detalles Bibliográficos
Autores principales: Okuda, Hiroko, Inoue, Sumiko, Oyamada, Yoshihiro, Koizumi, Akio, Youssefian, Shohab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161610/
https://www.ncbi.nlm.nih.gov/pubmed/37151704
http://dx.doi.org/10.1016/j.heliyon.2023.e15423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161610/
https://www.ncbi.nlm.nih.gov/pubmed/37151704
http://dx.doi.org/10.1016/j.heliyon.2023.e15423

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