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Reduced pain sensitivity of episodic pain syndrome model mice carrying a Nav1.9 mutation by ANP-230, a novel sodium channel blocker
The sodium channel Nav1.9 is expressed in the sensory neurons of small diameter dorsal root ganglia that transmit pain signals, and gain-of-function Nav1.9 mutations have been associated with both painful and painless disorders. We initially determined that some Nav1.9 mutations are responsible for...
Autores principales: | Okuda, Hiroko, Inoue, Sumiko, Oyamada, Yoshihiro, Koizumi, Akio, Youssefian, Shohab |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161610/ https://www.ncbi.nlm.nih.gov/pubmed/37151704 http://dx.doi.org/10.1016/j.heliyon.2023.e15423 |
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