Crystal engineering of ionic cocrystals comprising Na/K salts of hesperetin with hesperetin molecules and solubility modulation

Hesperetin (HES) is a weakly acidic flavonoid of topical interest owing to its antiviral properties. Despite the presence of HES in many dietary supplements, its bioavailability is hindered by poor aqueous solubility (1.35 µg ml(−1)) and rapid first-pass metabolism. Cocrystallization has evolved as...

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Detalles Bibliográficos
Autores principales: Jin, Shasha, Haskins, Molly M., Deng, Cheng-Hua, Matos, Catiúcia R. M. O., Zaworotko, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161764/
https://www.ncbi.nlm.nih.gov/pubmed/37079399
http://dx.doi.org/10.1107/S205225252300266X

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161764/
https://www.ncbi.nlm.nih.gov/pubmed/37079399
http://dx.doi.org/10.1107/S205225252300266X

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