Structural analysis of the Toll-like receptor 15 TIR domain

Toll-like receptors (TLRs) activate innate immunity in response to pathogen-associated molecular patterns (PAMPs). The ectodomain of a TLR directly senses a PAMP and the intracellular TIR domain dimerizes to initiate a signaling cascade. The TIR domains of TLR6 and TLR10, which belong to the TLR1 su...

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Detalles Bibliográficos
Autores principales: Ko, Kyung Yeol, Song, Wan Seok, Park, Jeongho, Lee, Geun-Shik, Yoon, Sung-il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161769/
https://www.ncbi.nlm.nih.gov/pubmed/37079400
http://dx.doi.org/10.1107/S2052252523002956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161769/
https://www.ncbi.nlm.nih.gov/pubmed/37079400
http://dx.doi.org/10.1107/S2052252523002956

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