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Structural analysis of the Toll-like receptor 15 TIR domain

Toll-like receptors (TLRs) activate innate immunity in response to pathogen-associated molecular patterns (PAMPs). The ectodomain of a TLR directly senses a PAMP and the intracellular TIR domain dimerizes to initiate a signaling cascade. The TIR domains of TLR6 and TLR10, which belong to the TLR1 su...

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Detalles Bibliográficos
Autores principales:	Ko, Kyung Yeol, Song, Wan Seok, Park, Jeongho, Lee, Geun-Shik, Yoon, Sung-il
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2023
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161769/ https://www.ncbi.nlm.nih.gov/pubmed/37079400 http://dx.doi.org/10.1107/S2052252523002956

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