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Mucosal p-STAT1/3 correlates with histologic disease activity in Crohn’s disease and is responsive to filgotinib

The validity and relevance of histologic disease activity in Crohn’s disease (CD) is unclear, owing to disconnects with endoscopic pathology. Here, we explore relationships between endoscopic, histologic, and molecular activity. This post hoc analysis of the Phase 2 FITZROY trial (NCT02048618) asses...

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Detalles Bibliográficos
Autores principales: Reinisch, Walter, Serone, Adrian, Hébuterne, Xavier, Kühbacher, Tanja, Kłopocka, Maria, Roblin, Xavier, Brodbeck, Jens, Etchevers, Kim, Galien, René, Grant, Ethan, Tasset, Chantal, Yoon, Oh Kyu, Zaboli, Shiva, Vermeire, Séverine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161938/
https://www.ncbi.nlm.nih.gov/pubmed/35762272
http://dx.doi.org/10.1080/21688370.2022.2088961