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Down syndrome: insights into autoimmune mechanisms

Understanding why individuals with Down syndrome are highly predisposed to autoimmunity has broad mechanistic and therapeutic implications. New work identifies novel potential mechanistic pathways driving increased autoimmunity-relevant CD11c(+) B cells and provides the broadest view to date of the...

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Detalles Bibliográficos
Autores principales: Khor, Bernard, Buckner, Jane H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161987/
https://www.ncbi.nlm.nih.gov/pubmed/37147460
http://dx.doi.org/10.1038/s41584-023-00970-0