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Structure of racemic duloxetine hydrochloride
Duloxetine hydrochloride (trade name Cymbalta) is marketed as a single enantiomer (S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propylaminium chloride, C(18)H(20)NOS(+)·Cl(−), which is twice as effective as the (R)-enantiomer in serotonin uptake. Here, we report the crystal structure...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162076/ https://www.ncbi.nlm.nih.gov/pubmed/37151834 http://dx.doi.org/10.1107/S2056989023003353 |