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An evolutionarily conserved bimodular domain anchors ZC3HC1 and its yeast homologue Pml39p to the nuclear basket

The proteins ZC3HC1 and TPR are structural components of the nuclear basket (NB), a fibrillar structure attached to the nucleoplasmic side of the nuclear pore complex (NPC). ZC3HC1 initially binds to the NB in a TPR-dependent manner and can subsequently recruit additional TPR polypeptides to this st...

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Detalles Bibliográficos
Autores principales: Gunkel, Philip, Iino, Haruki, Krull, Sandra, Cordes, Volker C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162418/
https://www.ncbi.nlm.nih.gov/pubmed/36857168
http://dx.doi.org/10.1091/mbc.E22-09-0402