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F-actin–rich territories coordinate apoptosome assembly and caspase activation during DNA damage–induced intrinsic apoptosis
The actin cytoskeleton is a ubiquitous participant in cellular functions that maintain viability, but how it controls programmed cell death is not well understood. Here we show that in response to DNA damage, human cells form a juxtanuclear F-actin–rich territory that coordinates the organized progr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162420/ https://www.ncbi.nlm.nih.gov/pubmed/36920061 http://dx.doi.org/10.1091/mbc.E22-04-0119 |