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Single-cell RNA sequencing reveals transcriptional changes of human choroidal and retinal pigment epithelium cells during fetal development, in healthy adult and intermediate age-related macular degeneration

Age-related macular degeneration (AMD) is the most prevalent cause of blindness in the developed world. Vision loss in the advanced stages of the disease is caused by atrophy of retinal photoreceptors, overlying retinal pigment epithelium (RPE) and choroidal endothelial cells. The molecular events t...

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Detalles Bibliográficos
Autores principales: Collin, Joseph, Hasoon, Megan S R, Zerti, Darin, Hammadi, Sarah, Dorgau, Birthe, Clarke, Lucy, Steel, David, Hussain, Rafiqul, Coxhead, Jonathan, Lisgo, Steven, Queen, Rachel, Lako, Majlinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162434/
https://www.ncbi.nlm.nih.gov/pubmed/36645183
http://dx.doi.org/10.1093/hmg/ddad007