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Geldanamycin treatment does not result in anti-cancer activity in a preclinical model of orthotopic mesothelioma

Mesothelioma is characterised by its aggressive invasive behaviour, affecting the surrounding tissues of the pleura or peritoneum. We compared an invasive pleural model with a non-invasive subcutaneous model of mesothelioma and performed transcriptomic analyses on the tumour samples. Invasive pleura...

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Detalles Bibliográficos
Autores principales: Orozco Morales, M. Lizeth, Rinaldi, Catherine A., de Jong, Emma, Lansley, Sally M., Lee, Y. C. Gary, Zemek, Rachael M., Bosco, Anthony, Lake, Richard A., Lesterhuis, W. Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162533/
https://www.ncbi.nlm.nih.gov/pubmed/37146029
http://dx.doi.org/10.1371/journal.pone.0274364