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Varying molecular interactions explain aspects of crowder-dependent enzyme function of a viral protease

Biochemical processes in cells, including enzyme-catalyzed reactions, occur in crowded conditions with various background macromolecules occupying up to 40% of cytoplasm’s volume. Viral enzymes in the host cell also encounter such crowded conditions as they often function at the endoplasmic reticulu...

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Detalles Bibliográficos
Autores principales: Ostrowska, Natalia, Feig, Michael, Trylska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162569/
https://www.ncbi.nlm.nih.gov/pubmed/37098073
http://dx.doi.org/10.1371/journal.pcbi.1011054