Potentiation of TRAIL-Induced Apoptosis in TRAIL-Resistant Cholangiocarcinoma Cells by Curcumin through the Induction of DR5 Membrane Localization and Disruption of the Anti-Apoptotic Complex DR5/DDX3/GSK3β

OBJECTIVE: Cholangiocarcinoma (CCA) is a cancer of the bile duct with a poor prognosis. The present study examined the ability of curcumin to sensitize apoptosis in the TNF-related apoptosis-inducing ligand (TRAIL)-resistant CCA cell lines of HuCCA-1 and KKU-213A. METHODS: Apoptosis was measured usi...

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Detalles Bibliográficos
Autores principales: Visitnonthachai, Daranee, Nakareangrit, Watanyoo, Suntararuks, Sumitra, Chaiyot, Kanjana, Watcharasit, Piyajit, Satayavivad, Jutamaad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162628/
https://www.ncbi.nlm.nih.gov/pubmed/36853289
http://dx.doi.org/10.31557/APJCP.2023.24.2.425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162628/
https://www.ncbi.nlm.nih.gov/pubmed/36853289
http://dx.doi.org/10.31557/APJCP.2023.24.2.425

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