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Potentiation of TRAIL-Induced Apoptosis in TRAIL-Resistant Cholangiocarcinoma Cells by Curcumin through the Induction of DR5 Membrane Localization and Disruption of the Anti-Apoptotic Complex DR5/DDX3/GSK3β
OBJECTIVE: Cholangiocarcinoma (CCA) is a cancer of the bile duct with a poor prognosis. The present study examined the ability of curcumin to sensitize apoptosis in the TNF-related apoptosis-inducing ligand (TRAIL)-resistant CCA cell lines of HuCCA-1 and KKU-213A. METHODS: Apoptosis was measured usi...
Autores principales: | Visitnonthachai, Daranee, Nakareangrit, Watanyoo, Suntararuks, Sumitra, Chaiyot, Kanjana, Watcharasit, Piyajit, Satayavivad, Jutamaad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
West Asia Organization for Cancer Prevention
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162628/ https://www.ncbi.nlm.nih.gov/pubmed/36853289 http://dx.doi.org/10.31557/APJCP.2023.24.2.425 |
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