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Microbial β-glucuronidases drive human periodontal disease etiology

Periodontitis is a chronic inflammatory disease associated with persistent oral microbial dysbiosis. The human β-glucuronidase (GUS) degrades constituents of the periodontium and is used as a biomarker for periodontitis severity. However, the human microbiome also encodes GUS enzymes, and the role o...

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Detalles Bibliográficos
Autores principales: Lietzan, Adam D., Simpson, Joshua B., Walton, William G., Jariwala, Parth B., Xu, Yongmei, Boynton, Marcella H., Liu, Jian, Redinbo, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162664/
https://www.ncbi.nlm.nih.gov/pubmed/37146137
http://dx.doi.org/10.1126/sciadv.adg3390