TMEM106B regulates microglial proliferation and survival in response to demyelination

TMEM106B, a lysosomal transmembrane protein, has been closely associated with brain health. Recently, an intriguing link between TMEM106B and brain inflammation has been discovered, but how TMEM106B regulates inflammation is unknown. Here, we report that TMEM106B deficiency in mice leads to reduced...

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Detalles Bibliográficos
Autores principales: Zhang, Tingting, Pang, Weilun, Feng, Tuancheng, Guo, Jennifer, Wu, Kenton, Nunez Santos, Mariela, Arthanarisami, Akshayakeerthi, Nana, Alissa L., Nguyen, Quynh, Kim, Peter J., Jankowsky, Joanna L., Seeley, William W., Hu, Fenghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162677/
https://www.ncbi.nlm.nih.gov/pubmed/37146150
http://dx.doi.org/10.1126/sciadv.add2676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162677/
https://www.ncbi.nlm.nih.gov/pubmed/37146150
http://dx.doi.org/10.1126/sciadv.add2676

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