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The Prognostic Effect of IKZF1 Deletions in ETV6::RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia

IKZF1 deletions are an established prognostic factor in childhood acute lymphoblastic leukemia (ALL). However, their relevance in patients with good risk genetics, namely ETV6::RUNX1 and high hyperdiploid (HeH), ALL remains unclear. We assessed the prognostic impact of IKZF1 deletions in 939 ETV6::R...

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Detalles Bibliográficos
Autores principales: Østergaard, Anna, Enshaei, Amir, Pieters, Rob, Vora, Ajay, Horstmann, Martin A., Escherich, Gabriele, Johansson, Bertil, Heyman, Mats, Schmiegelow, Kjeld, Hoogerbrugge, Peter M., den Boer, Monique L., Kuiper, Roland P., Moorman, Anthony V., Boer, Judith M., van Leeuwen, Frank N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162793/
https://www.ncbi.nlm.nih.gov/pubmed/37153875
http://dx.doi.org/10.1097/HS9.0000000000000875