Epiisopiloturine, an Alkaloid from Pilocarpus microphyllus, Attenuates LPS-Induced Neuroinflammation by Interfering in the TLR4/NF-κB-MAPK Signaling Pathway in Microglial Cells

Neuroinflammation is present in the pathophysiological mechanisms of several diseases that affect the central nervous system (CNS). Microglia have a prominent role in initiating and sustaining the inflammatory process. Epiisopiloturine (EPI) is an imidazole alkaloid obtained as a by-product of piloc...

Descripción completa

Detalles Bibliográficos
Autores principales: de Sousa, João Antônio Costa, Azul, Francisco Vinícius Clemente Serra, de Araújo, Ana Bruna, Tomé, Rebeca Colares, Silva, Francisca Raysse Mesquita, de Vasconcelos, Silvânia Maria Mendes, Rios, Francisco José, Leal, Luzia Kalyne Almeida Moreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162877/
https://www.ncbi.nlm.nih.gov/pubmed/37151606
http://dx.doi.org/10.1155/2023/4752502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162877/
https://www.ncbi.nlm.nih.gov/pubmed/37151606
http://dx.doi.org/10.1155/2023/4752502

Ejemplares similares