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Epigenomic mapping identifies an enhancer repertoire that regulates cell identity in bladder cancer through distinct transcription factor networks

Muscle-invasive bladder cancer (BLCA) is an aggressive disease. Consensus BLCA transcriptomic subtypes have been proposed, with two major Luminal and Basal subgroups, presenting distinct molecular and clinical characteristics. However, how these distinct subtypes are regulated remains unclear. We hy...

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Detalles Bibliográficos
Autores principales: Neyret-Kahn, Hélène, Fontugne, Jacqueline, Meng, Xiang Yu, Groeneveld, Clarice S., Cabel, Luc, Ye, Tao, Guyon, Elodie, Krucker, Clémentine, Dufour, Florent, Chapeaublanc, Elodie, Rapinat, Audrey, Jeffery, Daniel, Tanguy, Laura, Dixon, Victoria, Neuzillet, Yann, Lebret, Thierry, Gentien, David, Davidson, Irwin, Allory, Yves, Bernard-Pierrot, Isabelle, Radvanyi, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162941/
https://www.ncbi.nlm.nih.gov/pubmed/36944729
http://dx.doi.org/10.1038/s41388-023-02662-1