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DNA ultra-sensitive quantification, a technology for studying HIV unintegrated linear DNA

Unintegrated HIV DNA represents between 20% and 35% of the total viral DNA in infected patients. Only the linear forms (unintegrated linear DNAs [ULDs]) can be substrates for integration and for the completion of a full viral cycle. In quiescent cells, these ULDs may be responsible for pre-integrati...

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Detalles Bibliográficos
Autores principales: Roux, Hélène Marie, Figueiredo, Suzanne, Sareoua, Lucas, Salmona, Maud, Hamroune, Juliette, Adoux, Lucie, Migraine, Julie, Hance, Allan, Clavel, François, Cheynier, Rémi, Dutrieux, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162948/
https://www.ncbi.nlm.nih.gov/pubmed/37159665
http://dx.doi.org/10.1016/j.crmeth.2023.100443