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An inducible model for genetic manipulation and fate-tracing of PDGFRβ-expressing fibrogenic cells in the liver

Myofibroblasts are the source of extracellular matrix protein during liver fibrogenesis. Fibroblasts, hepatic stellate cells (HSCs) and vascular smooth muscle cells are mesenchymal subpopulations in the liver that are characterized by the expression of PDGFRβ and contribute to the pool of these myof...

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Detalles Bibliográficos
Autores principales: Hamberger, Florian, Mederacke, Young-Seon, Mederacke, Ingmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162963/
https://www.ncbi.nlm.nih.gov/pubmed/37147343
http://dx.doi.org/10.1038/s41598-023-34353-y