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An inducible model for genetic manipulation and fate-tracing of PDGFRβ-expressing fibrogenic cells in the liver
Myofibroblasts are the source of extracellular matrix protein during liver fibrogenesis. Fibroblasts, hepatic stellate cells (HSCs) and vascular smooth muscle cells are mesenchymal subpopulations in the liver that are characterized by the expression of PDGFRβ and contribute to the pool of these myof...
Autores principales: | Hamberger, Florian, Mederacke, Young-Seon, Mederacke, Ingmar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162963/ https://www.ncbi.nlm.nih.gov/pubmed/37147343 http://dx.doi.org/10.1038/s41598-023-34353-y |
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