Pancreatic β-cell glutaminase 2 maintains glucose homeostasis under the condition of hyperglycaemia

Glutaminase 2 (GLS2), a master regulator of glutaminolysis that is induced by p53 and converts glutamine to glutamate, is abundant in the liver but also exists in pancreatic β-cells. However, the roles of GLS2 in islets associated with glucose metabolism are unknown, presenting a critical issue. To...

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Detalles Bibliográficos
Autores principales: Deguchi-Horiuchi, Hanna, Suzuki, Sawako, Lee, Eun Young, Miki, Takashi, Yamanaka, Noriko, Manabe, Ichiro, Tanaka, Tomoaki, Yokote, Koutaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162969/
https://www.ncbi.nlm.nih.gov/pubmed/37147373
http://dx.doi.org/10.1038/s41598-023-34336-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162969/
https://www.ncbi.nlm.nih.gov/pubmed/37147373
http://dx.doi.org/10.1038/s41598-023-34336-z

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