The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma

Renal cancer cells constitute a paradigm of tumor cells with a glycolytic reprogramming which drives metabolic alterations favouring cell survival and transformation. We studied the expression and activity of pyruvate dehydrogenase kinases (PDK1-4), key enzymes of the energy metabolism, in renal can...

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Detalles Bibliográficos
Autores principales: Nunes-Xavier, Caroline E., Emaldi, Maite, Mingo, Janire, Øyjord, Tove, Mælandsmo, Gunhild M., Fodstad, Øystein, Errarte, Peio, Larrinaga, Gorka, Llarena, Roberto, López, José I., Pulido, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162970/
https://www.ncbi.nlm.nih.gov/pubmed/37147361
http://dx.doi.org/10.1038/s41598-023-34087-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162970/
https://www.ncbi.nlm.nih.gov/pubmed/37147361
http://dx.doi.org/10.1038/s41598-023-34087-x

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