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Optimal enzyme utilization suggests that concentrations and thermodynamics determine binding mechanisms and enzyme saturations

Deciphering the metabolic functions of organisms requires understanding the dynamic responses of living cells upon genetic and environmental perturbations, which in turn can be inferred from enzymatic activity. In this work, we investigate the optimal modes of operation for enzymes in terms of the e...

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Detalles Bibliográficos
Autores principales: Sahin, Asli, Weilandt, Daniel R., Hatzimanikatis, Vassily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162984/
https://www.ncbi.nlm.nih.gov/pubmed/37147292
http://dx.doi.org/10.1038/s41467-023-38159-4