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Senataxin and R-loops homeostasis: multifaced implications in carcinogenesis

R-loops are inherent byproducts of transcription consisting of an RNA:DNA hybrid and a displaced single-stranded DNA. These structures are of key importance in controlling numerous physiological processes and their homeostasis is tightly controlled by the activities of several enzymes deputed to pro...

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Detalles Bibliográficos
Autores principales: Gatti, Veronica, De Domenico, Sara, Melino, Gerry, Peschiaroli, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163015/
https://www.ncbi.nlm.nih.gov/pubmed/37147318
http://dx.doi.org/10.1038/s41420-023-01441-x