Microglial P2X4 receptors promote ApoE degradation and contribute to memory deficits in Alzheimer’s disease

Numerous evidences support that microglia contributes to the progression of Alzheimer’s disease. P2X4 receptors are ATP-gated channels with high calcium permeability, which are de novo expressed in a subset of reactive microglia associated with various pathological contexts, contributing to microgli...

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Detalles Bibliográficos
Autores principales: Hua, Jennifer, Garcia de Paco, Elvira, Linck, Nathalie, Maurice, Tangui, Desrumaux, Catherine, Manoury, Bénédicte, Rassendren, François, Ulmann, Lauriane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163120/
https://www.ncbi.nlm.nih.gov/pubmed/37145189
http://dx.doi.org/10.1007/s00018-023-04784-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163120/
https://www.ncbi.nlm.nih.gov/pubmed/37145189
http://dx.doi.org/10.1007/s00018-023-04784-x

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