SOST gene suppression stimulates osteocyte Wnt/β-catenin signaling to prevent bone resorption and attenuates particle-induced osteolysis

ABSTRACT: The most common cause for prosthetic revision surgery is wear particle-induced periprosthetic osteolysis, which leads to aseptic loosening of the prosthesis. Both SOST gene and its synthetic protein, sclerostin, are hallmarks of osteocytes. According to our previous findings, blocking SOST...

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Detalles Bibliográficos
Autores principales: Jiao, Zixue, Chai, Hao, Wang, Shendong, Sun, Chunguang, Huang, Qun, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163143/
https://www.ncbi.nlm.nih.gov/pubmed/37121919
http://dx.doi.org/10.1007/s00109-023-02319-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163143/
https://www.ncbi.nlm.nih.gov/pubmed/37121919
http://dx.doi.org/10.1007/s00109-023-02319-2

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