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A systematic review and meta-analysis of germline BRCA mutations in pancreatic cancer patients identifies global and racial disparities in access to genetic testing

BACKGROUND: Germline BRCA1 and BRCA2 mutations (gBRCAm) can inform pancreatic cancer (PC) risk and treatment but most of the available information is derived from white patients. The ethnic and geographic variability of gBRCAm prevalence and of germline BRCA (gBRCA) testing uptake in PC globally is...

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Detalles Bibliográficos
Autores principales: Paiella, S., Azzolina, D., Gregori, D., Malleo, G., Golan, T., Simeone, D.M., Davis, M.B., Vacca, P.G., Crovetto, A., Bassi, C., Salvia, R., Biankin, A.V., Casolino, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163165/
https://www.ncbi.nlm.nih.gov/pubmed/36822114
http://dx.doi.org/10.1016/j.esmoop.2023.100881