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The cytoplasmic N-terminal tail of Zika virus NS4A protein forms oligomers in the absence of detergent or lipids

The non-structural (NS) NS4A protein in flaviviruses has three predicted transmembrane domains, is critical for virulence and participates in membrane morphogenesis. In Dengue virus (DENV), both hydrophylic N-terminal tail and its first transmembrane domain participate in the formation of oligomers...

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Detalles Bibliográficos
Autores principales: Surya, Wahyu, Liu, Yiting, Torres, Jaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163220/
https://www.ncbi.nlm.nih.gov/pubmed/37147499
http://dx.doi.org/10.1038/s41598-023-34621-x