Scaffold repositioning of spiro-acridine derivatives as fungi chitinase inhibitor by target fishing and in vitro studies

The concept of “one target, one drug, one disease” is not always true, as compounds with previously described therapeutic applications can be useful to treat other maladies. For example, acridine derivatives have several potential therapeutic applications. In this way, identifying new potential targ...

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Detalles Bibliográficos
Autores principales: de Oliveira Viana, Jéssika, Silva e Souza, Eden, Sbaraini, Nicolau, Vainstein, Marilene Henning, Gomes, Joilly Nilce Santana, de Moura, Ricardo Olímpio, Barbosa, Euzébio Guimarães
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163251/
https://www.ncbi.nlm.nih.gov/pubmed/37147323
http://dx.doi.org/10.1038/s41598-023-33279-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163251/
https://www.ncbi.nlm.nih.gov/pubmed/37147323
http://dx.doi.org/10.1038/s41598-023-33279-9

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