Deletion of MIF gene from live attenuated LdCen(−/−) parasites enhances protective CD4(+) T cell immunity

Vaccination with live attenuated Leishmania parasites such as centrin deleted Leishmania donovani (LdCen(−/−)) against visceral leishmaniasis has been reported extensively. The protection induced by LdCen(−/−) parasites was mediated by both CD4(+) and CD8(+) T cells. While the host immune mediators...

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Detalles Bibliográficos
Autores principales: Fiuza, Jacqueline Araújo, Gannavaram, Sreenivas, Gaze, Soraya Torres, de Ornellas, Letícia Gambogi, Alves, Érica Alessandra, Ismail, Nevien, Nakhasi, Hira Lal, Correa-Oliveira, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163264/
https://www.ncbi.nlm.nih.gov/pubmed/37147351
http://dx.doi.org/10.1038/s41598-023-34333-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163264/
https://www.ncbi.nlm.nih.gov/pubmed/37147351
http://dx.doi.org/10.1038/s41598-023-34333-2

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