Cargando…
Deletion of MIF gene from live attenuated LdCen(−/−) parasites enhances protective CD4(+) T cell immunity
Vaccination with live attenuated Leishmania parasites such as centrin deleted Leishmania donovani (LdCen(−/−)) against visceral leishmaniasis has been reported extensively. The protection induced by LdCen(−/−) parasites was mediated by both CD4(+) and CD8(+) T cells. While the host immune mediators...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163264/ https://www.ncbi.nlm.nih.gov/pubmed/37147351 http://dx.doi.org/10.1038/s41598-023-34333-2 |