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Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma

Large-scale analyses of genomic data from patients with newly diagnosed multiple myeloma (ndMM) have been undertaken, however, large-scale analysis of relapsed/refractory MM (rrMM) has not been performed. We hypothesize that somatic variants chronicle the therapeutic exposures and clonal structure o...

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Detalles Bibliográficos
Autores principales: Ansari-Pour, Naser, Samur, Mehmet, Flynt, Erin, Gooding, Sarah, Towfic, Fadi, Stong, Nicholas, Estevez, Maria Ortiz, Mavrommatis, Konstantinos, Walker, Brian, Morgan, Gareth, Munshi, Nikhil, Avet-Loiseau, Herve, Thakurta, Anjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163277/
https://www.ncbi.nlm.nih.gov/pubmed/36223594
http://dx.doi.org/10.1182/blood.2022017010