Cargando…
Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma
Large-scale analyses of genomic data from patients with newly diagnosed multiple myeloma (ndMM) have been undertaken, however, large-scale analysis of relapsed/refractory MM (rrMM) has not been performed. We hypothesize that somatic variants chronicle the therapeutic exposures and clonal structure o...
Autores principales: | Ansari-Pour, Naser, Samur, Mehmet, Flynt, Erin, Gooding, Sarah, Towfic, Fadi, Stong, Nicholas, Estevez, Maria Ortiz, Mavrommatis, Konstantinos, Walker, Brian, Morgan, Gareth, Munshi, Nikhil, Avet-Loiseau, Herve, Thakurta, Anjan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163277/ https://www.ncbi.nlm.nih.gov/pubmed/36223594 http://dx.doi.org/10.1182/blood.2022017010 |
Ejemplares similares
-
The location of the t(4;14) translocation breakpoint within the NSD2 gene identifies a subset of patients with high-risk NDMM
por: Stong, Nicholas, et al.
Publicado: (2023) -
Loss of COP9 signalosome genes at 2q37 is associated with IMiD resistance in multiple myeloma
por: Gooding, Sarah, et al.
Publicado: (2022) -
Clinical features associated with COVID-19 outcome in multiple myeloma: first results from the International Myeloma Society data set
por: Chari, Ajai, et al.
Publicado: (2020) -
CDK7 controls E2F- and MYC-driven proliferative and metabolic vulnerabilities in multiple myeloma
por: Yao, Yao, et al.
Publicado: (2023) -
Spatiotemporal assessment of immunogenomic heterogeneity in multiple myeloma
por: Merz, Maximilian, et al.
Publicado: (2022)