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Tγδ LGLL identifies a subset with more symptomatic disease: analysis of an international cohort of 137 patients

Tγδ large granular lymphocyte leukemia (LGLL) is a rare variant of T-cell LGLL (T-LGLL) that has been less investigated as compared with the more frequent Tαβ LGLL, particularly in terms of frequency of STAT3 and STAT5b mutations. In this study, we characterized the clinical and biological features...

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Detalles Bibliográficos
Autores principales: Barilà, Gregorio, Grassi, Angela, Cheon, HeeJin, Teramo, Antonella, Calabretto, Giulia, Chahal, Jasmanet, Vicenzetto, Cristina, Almeida, Julia, Shemo, Bryna C., Shi, Min, Gasparini, Vanessa Rebecca, Munoz-Garcia, Noemi, Pastoret, Cédric, Nakazawa, Hideyuki, Oshimi, Kazuo, Sokol, Lubomir, Ishida, Fumihiro, Lamy, Thierry, Orfao, Alberto, Morice, William G., Loughran, Thomas P., Semenzato, Gianpietro, Zambello, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163282/
https://www.ncbi.nlm.nih.gov/pubmed/36096473
http://dx.doi.org/10.1182/blood.2021013489