The location of the t(4;14) translocation breakpoint within the NSD2 gene identifies a subset of patients with high-risk NDMM

Although translocation events between chromosome 4 (NSD2 gene) and chromosome 14 (immunoglobulin heavy chain [IgH] locus) (t(4;14)) is considered high risk in newly diagnosed multiple myeloma (NDMM), only ∼30% to 40% of t(4;14) patients are clinically high risk. We generated and compared a large who...

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Detalles Bibliográficos
Autores principales: Stong, Nicholas, Ortiz-Estévez, María, Towfic, Fadi, Samur, Mehmet, Agarwal, Amit, Corre, Jill, Flynt, Erin, Munshi, Nikhil, Avet-Loiseau, Hervé, Thakurta, Anjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163314/
https://www.ncbi.nlm.nih.gov/pubmed/35984902
http://dx.doi.org/10.1182/blood.2022016212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163314/
https://www.ncbi.nlm.nih.gov/pubmed/35984902
http://dx.doi.org/10.1182/blood.2022016212

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